Selected Publications
Johnson J, Meneses-Salas E, Shukla A, Shaji B, Rahman F, He J, Gavathiotis E, Brown S, Gonzalez-Quintial R, Hoffman H, Marquardt K, Teijaro J, Hedrick C, Baccala R, Rosen H, Catz S. Munc13-4–STX7 inhibitors impair endosomal TLR activation and systemic inflammation. Nat Chem Biol. 2026 Sep;22(9):1514-1527.
Askari K, Johnson JL, Shukla A, Meneses-Salas E, Kiosses WB, Yu J, Catz SD. Nexinhib20 inhibits JFC1-mediated mobilization of a subset of CD11b/CD18+ vesicles decreasing integrin avidity, but does not inhibit Rac1. J Leukoc Biol. 2025 Apr 23;117(4).
Yu J, Meneses-Salas E, Johnson JL, Manenti S, Ait Kbaich M, Chen D, Askari K, He J, Shukla A, Shaji B, Gonzalez-Quintial R, Croker BA, Zhang J, Hoffman H, Kiosses WB, Hedrick C, Pestonjamasp K, Wineinger N, Baccala R, Catz SD. Defective endomembrane dynamics in Rab27a deficiency impairs nucleic acid sensing and cytokine secretion in immune cells. Cell Rep. 2024;43:114598.
Rahman F, Johnson JL, Ait Kbaich M, Meneses-Salas E, Shukla A, Chen D, Kiosses WB, Gavathiotis E, Cuervo AM, Cherqui S, Catz SD. Reconstitution of Rab11-FIP4 expression rescues cellular homeostasis in cystinosis. Mol Cell Biol. 2024;44(12):577-589.
Catz SD. Divergent mechanisms of inflammasome activation in neutrophil early response and inflammation. Nat Immunol. 2023;24:1970-1971.
Johnson JL, Meneses-Salas E, Ramadass M, Monfregola J, Rahman F, Gontijo RC, Kiosses WB, Pestonjamasp K, Allen DJ, Zhang J, Osborne D, Zhu YP, Wineinger NE, Askari K, Chen D, Yu J, Henderson SC, Hedrick CC, Ursini MV, Grinstein S, Billadeau DD, Catz SD. Differential dysregulation of granule subsets in WASH-deficient neutrophil leukocytes resulting in inflammation. Nat Commun. 2022.
Rahman F, Johnson JL, Zhang J, He J, Pestonjamasp K, Cherqui S, Catz SD. DYNC1LI2 regulates localization of the chaperone-mediated autophagy receptor LAMP2A and improves cellular homeostasis in cystinosis. Autophagy. 2022 May;18(5):1108-1126.
Johnson JL, Ramadass M, Rahman F, Meneses-Salas E, Zgajnar NR, Gontijo RC, Zhang J, Kiosses WB, Zhu YP, Hedrick CC, Perego M, Gunton JE, Pestonjamasp K, Napolitano G, Catz SD. The atypical small GTPase GEM/Kir is a negative regulator of the NADPH oxidase and NETs production through macroautophagy. J Leukoc Biol. 2021;110:629-649.
Zeng F, Chen Z, Chen R, Shufesky WJ, Bandyopadhyay M, Camirand G, Oberbarnscheidt MH, Sullivan ML, Baty CJ, Yang MQ, Calderon M, Stolz DB, Erdos G, Pelanda R, Brennan TV, Catz SD, Watkins SC, Larregina AT, Morelli AE. Graft-derived extracellular vesicles transported across subcapsular sinus macrophages elicit B cell alloimmunity after transplantation. Sci Transl Med. 2021;13:eabb0122.
Catz SD, McLeish KR. Therapeutic targeting of neutrophil exocytosis. J Leukoc Biol. 2020;107:393-408.
Karmakar M, Minns M, Greenberg EN, Diaz-Aponte J, Pestonjamasp K, Johnson JL, Rathkey JK, Abbott DW, Wang K, Shao F, Catz SD, Dubyak GR, Pearlman E. N-GSDMD trafficking to neutrophil organelles facilitates IL-1 beta release independently of plasma membrane pores and pyroptosis. Nat Commun. 2020;11:2212.
Recent Professional Activities
2026 Chair elected, “Neutrophil Biennial International Symposium”
2024 Editor, Journal of Leukocyte Biology
2023 Chair elected, Gordon Research Conference-Phagocytes 2023
2023 Chair (ad hoc) NIH, CSF1 study section
2023 NIH, CSF1 study section permanent member
2021 Vice Chair elected, Gordon Research Conference-Phagocytes 2021
2021 Co-Chair, Search committee for managing Editor, Journal of Leukocyte Biology
2019-2024 Council Society for Leukocyte Biology
2019 - 2025 NIH, MBPP study section, permanent member, NIH
2016 - current Editorial Review Board, Cystinosis Research Foundation
2014 - current Editorial board member, Journal of Biological Chemistry